How do you create a profile in ION ?

[Phanx]

You don't. Ion does not (yet) support profiles of any kind. Maul (the author of Ion) does not seem to have time to work on finishing the addon anymore. You are probably better off switching to another addon that is actively developed and maintained.

I switched to Bartender4 when MoP came out, and have been pretty happy with it. It doesn't support macro buttons, but there are plenty of addons that give you more/longer macros that you can use with it, if you really can't fit your macros into the space the Blizzard macro system gives you.