[LudiusMaximus]

If you know the name of your frame (e.g. YourFrame), try this:

YourFrame:HookScript("OnShow",
  function(self)
    if not self:IsProtected() or not InCombatLockdown() then
      self:SetPoint("BOTTOMRIGHT", UIParent, "BOTTOMRIGHT", -500, 500)
    end
  end)