It depends on what you want - if you want good AV, keep using Kaspersky, MS Security Essentials, or NOD32....if you don't care as much about using one of the best AV programs, dump Kaspersky and get McAfee, AVG, etc.
IMO, keeping a better VA, and manually updating addons is better than reducing your AV protection (by going with the likes of McAfee, AVG, etc) and having something automatically do it for you.
Check the AV Comparatives site for comparison checks of a majority of the AV applications out.
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Marth
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