[Dridzt]

local UnitAffectingCombat, InCombatLockdown = UnitAffectingCombat, InCombatLockdown
 
local function hide(self)
    if TipBeGone.CombatOnly then
        if (UnitAffectingCombat("player") or UnitAffectingCombat("pet") or InCombatLockdown()) then
            self:Hide()
        end
    else
        self:Hide()
    end
end
 
local function thide(self)
    hide(GameTooltip);
end
 
-- Hide tooltips for actions, pet actions and shapeshift
if TipBeGone.ActionBar then
    hooksecurefunc(GameTooltip, "SetAction", hide);
end
if TipBeGone.PetActionBar then
    hooksecurefunc(GameTooltip, "SetPetAction", hide);
end
if TipBeGone.ShapeShiftBar then
    hooksecurefunc(GameTooltip, "SetShapeshift", hide);
end
 
-- Hide tooltips for inventory items (paper doll and inspect)
if TipBeGone.Inventory then
    hooksecurefunc(GameTooltip, "SetInventoryItem", hide); 
end
 
-- Hide tooltips on micro buttons
if TipBeGone.MainBar then
    CharacterMicroButton:HookScript("OnEnter", thide)
    SpellbookMicroButton:HookScript("OnEnter", thide)
    TalentMicroButton:HookScript("OnEnter", thide)
    QuestLogMicroButton:HookScript("OnEnter", thide)
    MainMenuMicroButton:HookScript("OnEnter", thide)
    PVPMicroButton:HookScript("OnEnter", thide)
    SocialsMicroButton:HookScript("OnEnter", thide)
    GuildMicroButton:HookScript("OnEnter", thide) -- Cataclysm
    LFDMicroButton:HookScript("OnEnter", thide)
    HelpMicroButton:HookScript("OnEnter", thide)
    AchievementMicroButton:HookScript("OnEnter", thide)
end
 
-- Hide tooltips on bag and keyring buttons
if TipBeGone.Bags then
    MainMenuBarBackpackButton:HookScript("OnEnter", thide);
    CharacterBag0Slot:HookScript("OnEnter", thide);
    CharacterBag1Slot:HookScript("OnEnter", thide);
    CharacterBag2Slot:HookScript("OnEnter", thide);
    CharacterBag3Slot:HookScript("OnEnter", thide);
    KeyRingButton:HookScript("OnEnter", thide);
end

Maybe something like this...