[Vrul]

Using functions:

function CFM_ToggleSetting(self, prop)
	local setting = activeProfile[selName]
	local frame = _G[setting.frame]
	local value = self:GetChecked() == 1
	local func
	if prop == "disableMouse" then
		func = frame.EnableMouse
	elseif prop == "clamp" then
		func = frame.SetClampedToScreen
	end
	setting[prop] = value
	func(frame, value)
end

Using methods:

function CFM_ToggleSetting(self, prop)
	local setting = activeProfile[selName]
	local frame = _G[setting.frame]
	local value = self:GetChecked() == 1
	local method
	if prop == "disableMouse" then
		method = "EnableMouse"
	elseif prop == "clamp" then
		method = "SetClampedToScreen"
	end
	setting[prop] = value
	frame[method](frame, value)
end